Pediatric Brain Tumor Foundation
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Research News

03/08/19

Study Results: Immunotherapy Drug Shows Promise for Adult Glioblastoma Patients When Treated Before Surgery

02/06/19

Pediatric Brain Tumor Foundation Responds to State of the Union and the Need for More Government Funding for Childhood Cancer Research

01/16/19

Pediatric Brain Tumor Foundation Joins Other Members of Brain Tumor Funders’ Collaborative in Announcing $3 Million in Research Grants

01/07/19

Study Results: Liquid Biopsy Blood Test Shows Promise for Detecting Genetic Changes in Pediatric Brain Tumors

11/20/18

New Study: Radiation-associated Cognitive Decline Prevented in First Animal Model of Glioma

11/13/18

Pediatric Brain Tumor Foundation and A Kids’ Brain Tumor Cure Join Forces to Change the Outcome for All Children with Brain Cancer

11/08/18

New “Multi-Omic” Research Projects Launched to Confront the Complexity of Glioblastoma and Pediatric Brain Tumor Treatment Development
This week, the National Cancer Institute (NCI), the U.S. government’s principal agency for cancer research, announced funding for new adult and pediatric brain cancer research projects. The funding, totaling $4 million, was driven by the leadership of the NCI and concerted advocacy efforts of the U.S. brain tumor community, led by the Eliminate Cancer Initiative (ECI), the National Brain Tumor Society (NBTS), and the Pediatric Brain Tumor Foundation (PBTF).

09/04/18

Christopher Brandle Joy of Life Foundation and PBTF Partner Again to Fund Cutting-Edge Medulloblastoma Research
The Pediatric Brain Tumor Foundation (PBTF) has received a $150,000 grant from the Christopher Brandle Joy of Life Foundation (CBJOLF) to fund medulloblastoma research at Massachusetts General Hospital.

07/02/18

Phase 1b Clinical Trial for Genetically Modified Poliovirus Therapy Enrolling Children and Teens at Duke University

05/31/18

Researchers and Pediatric Brain Tumor Nonprofits Gather in Portland for 2018 Translating Discoveries to Cure the Kids

09/28/17

St. Jude Study Reveals Chronic Health Conditions Are Most Prevalent in Survivors of Pediatric Central Nervous System Cancers
A study by St. Jude has revealed that the extent of chronic health conditions in adult childhood cancer survivors is significantly more substantial than those in the general public. The results of this extensive research can be used to better inform future clinical guidelines, research investigations and health services planning for childhood cancer survivors.

07/27/17

NCI-COG Pediatric MATCH Trial Opens for Enrollment
A long-awaited and first-of-its-kind precision medicine clinical trial in childhood cancer is now open for enrollment. NCI-COG Pediatric Molecular Analysis for Therapy Choice (Pediatric MATCH) will explore the effectiveness of targeted therapies in children and adolescents with brain and other solid tumors.

07/20/17

Medulloblastoma Study Reveals New Subtypes of Malignant Childhood Brain Tumor
A new study published in Nature has uncovered a series of previously undiscovered medulloblastoma subtypes. The results of this latest research are expected to help advance new treatments for this highly malignant brain tumor that predominantly occurs in childhood.

04/06/17

Meet the Experts Brings Together Chicago Medical Community and Pediatric Brain Tumor Families to Learn and Network
To help answer families’ questions about childhood brain tumor treatments and the challenges that may follow, the Pediatric Brain Tumor Foundation’s Meet the Experts program brings together medical experts and parent experts across the country.

03/23/17

PBTF Grant Awardee to Run Neuro-Oncology Program at Rady Children’s Hospital
Rady Children’s Hospital - San Diego has named Dr. Robert Wechsler-Reya program director of the Joseph Clayes III Research Center for Neuro-Oncology and Genomics.

03/17/17

UC San Diego Bioengineers Developing Potential Blood Test for Early Cancer Detection
A new blood test being developed by bioengineers at the University of California San Diego could provide a way to diagnose cancer early on without invasive surgical procedures.

11/30/16

Early clinical trial results of dabrafenib positive for children with low-grade glioma
Early clinical trial results are positive for dabrafenib (Taflinar®), a candidate targeted therapy for children with low-grade glioma (LGG). The drug targets a mutation called BRAF V600E that occurs in several tumor types, including about 10 percent of LGGs. – Vector, Boston Children’s Hospital's science and clinical innovation blog

10/20/16

Promising results of clinical study in pediatric low-grade glioma
Researchers report positive results for the first clinical study of dabrafenib, a targeted therapy, for pediatric low grade-grade glioma. Participants in this small study represent the subset of pediatric low-grade glioma patients whose tumors have a BRAF mutation.

10/20/16

Cancer Moonshot report highlights new collaboration involving PBTF awardee, PNOC
The PBTF-funded Pacific Pediatric Neuro-Oncology Consortium (PNOC) and the Children’s Brain Tumor Tissue Consortium (CBTTC) announce a partnership that promises to radically pick up the pace of pediatric cancer research. Together with Seven Bridges, they have launched CAVATICA, a cloud-based platform that enables scientists around the globe to collaborate more effectively. This joint endeavor answers a call by the Cancer Moonshot initiative to de-silo data and enable rapid access and analysis of genomic and other types of data for discovery research.

09/16/16

Brain cancer now deadliest childhood cancer
Brain cancer has replaced leukemia as the No. 1 cancer killer of children and adolescents ages 1-19, according to a new report from the U.S. government. – CDC