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Research News

07/11/14

Biomarker predicts effectiveness of brain cancer treatment
New research from the University of California, San Diego School of Medicine may help determine which glioblastoma patients will benefit most from temozolomide chemotherapy. Currently, all glioblastoma patients are treated with temozolomide, but only 15 percent of them experience long-lasting benefits.

07/03/14

New genes that promote cancer discovered
Researchers at Sanford-Burnham Medical Research Institute and 36 other institutes have discovered two oncogenes that cause childhood brain cancer when activated. This may eventually allow doctors to adjust therapies for medulloblastoma patients to target the genes that are actually causing the growth of the tumor. – Sanford-Burnham

06/17/14

Phase I trial tolerated well by children with CNS tumors
A study of a phase I trial in 29 children with recurrent central nervous system tumors shows that when treated with the drug combination, veliparib and temozolomide, the patients tolerated treatment well. The phase I/II portion of the study includes radiation and is in progress in patients with newly diagnosed brainstem gliomas. – Oxford Journals

06/17/14

Study may lead to new brain cancer treatment delivery method
Researchers at Mayo Clinic have developed a synthetic peptide carrier that can cross the blood-brain barrier. Findings may lead to a new delivery method for brain cancer treatment. – Mayo Clinic News Network

06/05/14

ASCO aims for reverse in decline of federal cancer research funding
The American Society of Clinical Oncology, along with partners in the cancer community, is calling on Congress to renew commitment to federal funding of cancer research. Their goal is to help reverse the decline in federal funding. – ASCO Daily News

06/05/14

Duke Medicine, Chinese researchers identify genetic mutation
Collaboration between Duke Medicine researchers and neurosurgeons and scientists in China has led to new insights into brainstem gliomas. The researchers identified a genetic mutation in tumor cells that causes cells to keep dividing and avoid death. – Duke Medicine

06/05/14

Cancer researchers need to be bold, scientists say
Isaac S. Chan, PhD, and William R. Jeck, PhD, say researchers must be willing to seek new ideas and be bold when researching cancer. – News & Observer

05/22/14

Researchers use herpes to treat brain cancer
Researchers at the Harvard Stem Cell Institute at Massachusetts General Hospital have found that by trapping herpes-loaded stem cells in a gel and applying them to tumors, they were able to significantly improve the survival rate of mice with glioblastoma multiforme brain tumors. The method is predicted to enter human trials in two to three years. – Medical Daily

05/22/14

Scientists create new method to treat tumors
Scientists have created a new approach to treating tumors, using patients’ own immune systems. The tailored method may lead to therapy treatments for 80 percent of all cancers. – Medical Daily

03/21/14

Parents donate child’s tumor tissue to research
After losing their 6-year-old son to DIPG, parents Lenore and Trevor Wyant donated his tumor tissue to research, hoping to find answers for other children battling the disease. Because of donated tissue samples, scientists were able to conduct the studies that led to the discovery reported in 2012, that unique genetic mutations are present in 80 percent of DIPG samples. –USA Today

03/21/14

Childhood cancer survivors face more health issues in adulthood
According to a federally funded study led by researchers at St. Jude Children's Research Hospital, adult survivors of childhood cancer face significant health problems as they age. The study shows that these survivors are five times more likely than their siblings to develop new cancers beyond the age of 35. –Science Daily