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Research News

07/02/15

Study compares results of chemotherapy drugs administered during radiation
A feasibility study compares the effectiveness of chemotherapy drugs administered during radiation treatment in childhood high-grade gliomas. The outcome showed that temozolomide performed best. – Oxford Journals

06/25/15

High dose radiation may improve survival in childhood ependymoma
Two studies show that children with intracranial ependymoma who are given a high dose of radiation experience improved survival rates. – ecancer

06/18/15

‘Tumor paint’ approved for testing in children
A dye that comes from scorpion venom, known as “tumor paint,” can illuminate cancer cells so doctors can more easily see them for removal during surgery. The dye has been approved for safety testing in a small study in children and young adults. – The Seattle Times

06/04/15

Experts discuss role of pediatric palliative care in community
Historically, pediatric palliative care has taken place in a hospital setting. Today, experts discuss the importance of community-based pediatric palliative care programs and the benefits to patients. – Wiley Online Library

05/28/15

Physician calls for better palliative care for children
Joanne Wolfe, MD, MPH, of Dana-Farber Cancer Institute and Boston Children’s Hospital, seeks a better way to care for sick children and their families. Wolfe insists on greater support for families during each stage of a child’s illness. – Cognoscenti

05/21/15

Experimental drug attacks brain tumor tissue
Researchers are currently testing a drug called MP-MUS that attacks brain tumor tissue, yet does not appear to affect healthy brain cells grown in the lab. Unlike chemotherapy in general, this drug works by affecting mitochondrial DNA rather than DNA in the nucleus. – EurekAlert!

05/14/15

Potential treatment for DIPG identified
Based on studies in the lab using cultured tumor cells from patients, a group of international scientists has found that the drug panobinostat, and other similar gene-regulating drugs, may be effective at treating diffuse intrinsic pontine gliomas. – National Institutes of Health

02/05/15

PBTF helps conduct study that examines potential years of life lost in young brain tumor patients
In the realm of childhood cancers, incidence and survival rates are commonly reported statistics, but these may fail to capture the full impact of the disease. In a new study, researchers, including PBTF’s vice president of research, describe the years of potential life lost and years of life lived with disease in children and adolescents who died of cancer in the United States. – Cancer Medicine Journal

08/21/14

Cancer community concerned about EU proposal
A recent European Parliament resolution may impose that researchers be required to ask for a patient's ‘specific’ consent each time new research is carried out on already available data and/or tissues. The unintended consequence of the wording may put at stake the practice of retrospective clinical research, tissue banking and population-based cancer registries.

03/21/14

Parents donate child’s tumor tissue to research
After losing their 6-year-old son to DIPG, parents Lenore and Trevor Wyant donated his tumor tissue to research, hoping to find answers for other children battling the disease. Because of donated tissue samples, scientists were able to conduct the studies that led to the discovery reported in 2012, that unique genetic mutations are present in 80 percent of DIPG samples. –USA Today

03/21/14

Childhood cancer survivors face more health issues in adulthood
According to a federally funded study led by researchers at St. Jude Children's Research Hospital, adult survivors of childhood cancer face significant health problems as they age. The study shows that these survivors are five times more likely than their siblings to develop new cancers beyond the age of 35. –Science Daily