Pediatric Brain Tumor Foundation
Working to eliminate the challenges
of childhood brain tumors
Please leave this field empty

Cure the kids! Give Now

font size AAA

Apply for Research Funding

The Pediatric Brain Tumor Foundation is leading the way in transforming how childhood brain tumors are treated and how children, teens, and their families are cared for. Our research programs provide critical funding that will help address key gaps in the research and drug development pipeline to accelerate therapies and ultimately find a cure for all pediatric brain tumors.

We are currently welcoming proposals for the following grants. For eligibility guidelines and application information, please review the research funding opportunities below.

Request for Proposals: Drug Delivery Research in Pediatric Neuro-oncology

NOTE: This RFP was updated on March 23, 2020 to reflect an extension of the periods of application submission and project start date. Updated timeline can be found below and in the linked RFP. Please email jsalcido@curethekids.org with any questions.

Award: $200,000 over 2 years
Application Deadline: Letters of Intent due July 6, 2020; Full Proposals (finalists only) due October 26, 2020
Decision Date: December 16, 2020

View the Request for Proposals here.
Submit a Letter of Intent here.

Drug delivery is a major challenge to effectively translating validated laboratory findings into clinical success against brain and central nervous system tumors. Variables such as blood-brain barrier and blood-tumor barrier penetration and the distribution of drugs through the brain parenchyma to tumor cells pose significant obstacles to treating all brain tumor types.

Guided by input from the Pediatric Brain Tumor Foundation’s Research Advisory Network and discussions at the foundation’s 2019 Translating Discoveries to Cure the Kids (TD2) research conference, the PBTF requests proposals for research that will advance innovative platforms for enhancing or evaluating drug delivery and/or distribution.

The proposed research must focus on drug delivery for treating brain tumors in children. Research proposals of special interest to the PBTF are ones likely to generate findings instrumental to advancing treatment options or assessing treatment efficacy.

Apply for a PLGA Fund Grant (Ongoing Basis)

The PLGA Fund at the Pediatric Brain Tumor Foundation fuels the most promising pediatric low-grade glioma and astrocytoma research. The number one priority of the PLGA Fund at PBTF is to act as a catalyst for researchers worldwide to turn their attention to the area of pediatric low-grade glioma brain tumor research and to award research grants for the most promising programs and studies. Our hope is that this research will lead to a better understanding of the causes of PLGG/PLGA, as well as the discovery of more effective treatments and a cure for the most common forms of childhood brain tumors.

  • Novel concepts/hypotheses are encouraged, and a premium is given to projects which involve collaboration between institutions and investigators. 
  • Eligible projects include basic science, translational and clinical trial initiatives, as well as survivorship/outcomes studies.  
  • Project funding is awarded over one, two or three-year periods depending on scope and complexity of project.
  • Investigators in the early years of their careers are encouraged to apply.

TIMING

The PLGA Fund at PBTF awards grants on an ongoing basis throughout the year.  There are no deadlines.  We encourage investigators to apply at their earliest convenience.

LETTER OF INTENT CRITERIA

Investigators from all over the world are invited to submit a ‘Letter of Intent’ at any time throughout the year to the Pediatric Brain Tumor Foundation at plgaresearch@curethekids.org. This ‘Letter of Intent’ should contain:

  • A brief synopsis
  • Specific project aims 
  • Potential outcomes for the proposed study
  • Project timetable (high level)
  • Budget (high level)
  • Collaborating institutions/Investigators

This document will be reviewed by the Pediatric Brain Tumor Foundation’s PLGA Scientific Advisory Board and a selected group of applicants will then be invited to submit a full proposal based on this feedback.

Only proposals with the highest scores demonstrating the most potential to have a significant impact on the future of children with PLGG/PLGA tumors will be awarded. Award funding is based on size, impact and complexity of project.

The guidelines, forms and requirements for the grant proposal will be provided when pre-applicants are notified of solicitation.

The PLGA Fund at PBTF also collaborates with other organizations in the childhood cancer arena.

GRANT CONDITIONS

  • Grant recipients are required to submit progress reports to the PLGA Fund on an agreed upon basis (typically annually).
  • Grantees must acknowledge the Pediatric Brain Tumor Foundation’s support in all publications about the research.
  • No grants will be made to private individuals.
  • All grants are awarded with the understanding of 0% overhead.
  • PLGA Fund grant awards do not cover debt reduction, capital improvements or travel expenses.
  • Grant recipients must be willing to collaborate with other PLGA Fund grant recipients when appropriate.
  • Previous PLGA Fund grant recipients are eligible to apply.

Please email us at plgaresearch@curethekids.org with any questions or for further information.