Pediatric Brain Tumor Foundation
Working to eliminate the challenges
of childhood brain tumors
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Research Funding Programs

The PBTF funds research through four programs -- its Immunotherapy Research Initiative, PLGA Fund at PBTF, Early Career Development and Opportunity grants. This research will increase our knowledge of the biology of brain tumors in childhood and enable breakthroughs in the development of lifesaving and less toxic treatment strategies.

Immunotherapy Research Initiative
Immunotherapy brings new hope to cancer treatment, and the Pediatric Brain Tumor Foundation’s Immunotherapy Research Initiative will level the playing field for children with brain tumors. The PBTF plans to invest a total of $2 million over three years to advance research through this two-part initiative. This large-scale investment will generate new discoveries specific to pediatric brain tumors, inform future immunotherapy research in the field, and be relevant across different types of immunotherapy and pediatric brain tumors.

Immunotherapy Research Initiative details >>

The PBTF and A Kids' Brain Tumor Cure have partnered to launch a new research program that continues AKBTC's mission of fueling the most promising pediatric low-grade glioma and astrocytoma research. Over the past decade, the AKBTC’s research seed funding has enabled scientists to apply and win multi-million-dollar grants from the National Cancer Institute and resulted in five new clinical trials that have helped shape the direction for targeted therapies. The PLGA Fund at PBTF continues this funding of research that will lead to non-toxic, non-invasive treatments and, ultimately, a cure. Research proposals are currently being accepted; eligible projects include basic science, translational and clinical trial initiatives.

PLGA Fund at PBTF details >>

Early Career Development Grants
The goal of the PBTF’s Early Career Development grants program is to support talented researchers in the field of pediatric brain tumors who are in the first five years of their first faculty position. The expectation is that this funding will facilitate awardees’ transition to becoming fully independent investigators.

We issued a request for proposals in fall 2014. Applications were robustly reviewed by a scientific review team specifically assembled for this program. Proposals were evaluated on the merit of the:

  • Mentorship and research environment
  • Researcher’s productivity to date and career plan
  • Proposed research project

ECD awardees and project summaries >>

Opportunity Grants
Research initiatives that we judge to be critical to filling in the gaps and enhancing the pediatric brain tumor research landscape are eligible for opportunity grants.

Discussions with our Research Advisory Network and the broader scientific community help us identify candidates for funding. Applications are accepted by invitation only. However, we welcome discussion of research ideas that fit with our strategic priorities, particularly if the ideas involve multi-institutional efforts.

Opportunity awardees and project summaries >>

Grant Recipients
The PBTF has supported projects at major research institutions around the world.

Read about our additional grant funding >>