What We Fund
Research funded by the PBTF has attracted more scientists to the field.
The Pediatric Brain Tumor Foundation believes that outcomes for children with brain tumors will improve more quickly when researchers share the results of their work with each other in real time and work collaboratively.
This belief forms the basis of the Institute program launched in 2003. By design, we concentrated our investment in select group of centers with well-recognized expertise in pediatric brain tumor research.
The Institute model offers several advantages, including enhanced coordination of discovery and translational research efforts, greater sharing and leveraging of core resources between institutions, flexibility in project prioritization based on results, and enhanced exchange of experimental findings and approaches between principal investigators.
PBTF Institutes and Investigators
Director: Darell Bigner, MD, PhD
Lead investigators: Oren Becher, MD, Wei Chen, PhD, Mark Dewirst, PhD, Henry Friedman, MD, Matthias Gromeier, MD, Yiping He, PhD, Sally Kornbluth, PhD, Chien-Tsun Kuan, PhD, Roger McLendon, MD, John Sampson, MD, PhD, and Michael Zalutsky, PhD.
Hospital for Sick Children, Canada
Director: James Rutka, MD, PhD
Lead investigator: Michael Taylor, MD, PhD.
University of California, San Francisco
Director: Mitchel Berger, MD
Co-director: Nalin Gupta, MD, PhD
Lead investigators: Arturo Alvarez-Buylla, PhD, C. David James, PhD, Joanna Phillips, MD, PhD, David Rowitch, MD, PhD, William Weiss, MD, PhD.
Representing an annual investment of $1.8 million in 2013 and 2014, the PBTF is funding research on 20 projects at our Institutes, as well as a research project in the laboratory of Bert Vogelstein, MD, at the Johns Hopkins Medical Institute.
Funding also supports core resources at the UCSF and Duke PBTF Institutes, including banked patient tumor tissue, cell lines and rodent models of pediatric brain tumors.
The Pediatric Brain Tumor Foundation has a long history of awarding funding to many institutions and organizations conducting a broad spectrum of basic/discovery and translational research.
We also sponsor scientific meetings at which the latest developments are discussed and new collaborative research efforts are often forged to advance the search for the cause of and cure for childhood brain tumors.
In addition, we provide funding to the Central Brain Tumor Registry of the United States, which works with population-based registries to track all primary brain and central nervous system tumors diagnosed in the United States. The data are published in an annual statistical report.
The PBTF also provided a founding grant to the Society of Neuro-Oncology to establish the medical journal Neuro-Oncology, which is now rated as one of the top medical journals of its kind.